Picking up where Sin left off, players are thrown once again into the role of super-cop John Blade. A new wave of terror has infested the city of Freeport and the U4 chemical (DNA altering) is once again a problem. To make it worse, the crime lord behind all this has kidnapped a very important scientist?s daughter and it will be up to you to bring her back alive. And how will you do this? By rampaging and shooting your way through seventeen brand new mission-styled levels. New weapons are dual magnums, a flame-thrower and concussion rifle, plasma bow and something that can only be described as BFG-like.